Antipsychiatry Drugs Review

Anti psy drugs…mech of action..

Typ

More potency more extra pyr effects less sed

Block dop receptors at BG soo more extra pyr effect

ATYp

Less potency less extra pyr more sed

Risp acts on D2

Clozapine D 4

SIDE EFFECTS

ANTI CHOL…..dry mouth confusion urin retention

constipation delirium blur vision

CARDIAC…..risperidone increases QT interval sooo card ARRY

HYPOTENTION…..rispe….due 2 alpha receptor blocked

Mostly due 2 low potency drugs

SEDATION……due to anti his effect

AGRAN….d/t clozapine

ENDO…..resp….gynaecomastia..ammen….galactoria

DERMAL & OCULAR…..esp thioridazine…pig retinopathy….

REDUCED SEIZURE THREAHOLd….esp clozapine…

WEIGHT GAIN…..olazapine

MOVEMENT DISORDERS acute

PARK(bradykinesia)

Slow movement increase mle tone resting tremors….

Mostly in elderly

Treat with

Anti chol like tri hexyphenidly or benztropin

ACUTE DYSTONIA

Spasm of musle groups like oculogyric….buccolingual ..opthithotonus…..

Mostly in young….

Treat by

Anti chol like benztropin ..I/V opr I/M

AKATHASIA

Restlessness…treat with

Propranalol…

TARD DYSKINASIA

Choreoathetosis…invol mm…first of tongue & fingers then trunk

Switch 2 clozapin….

MALIG NEUROLEPTIC SYN

Mle rigitidy & increased temp..

Giv dantrolene & bromo

SOME IMP SIDE EFFECT

Thioridazine….photo sen & pig retinopathy & retrogardae ejac…

& galac..ammen

Clozapine…..agran …seizure….sed….wt gain..sialoorrhea…

Risp….less sed less extra ..less anti chol

Quetrapine…cataract

TREATMENTS….

For psycho motor agi & delusion…………….HALO 5mg I/M hourly some add lorazepam

For SCHIZO…. Resp

Delirium……..HALO

Dementia…..resp

ALZ………..resp.

HUNTINGtonz…....HALOPER...

(Taken from Internet Site)