·
Fenofibrate,
which is least likely to interfere with statin metabolism, appears to be the safest fibrate to use with statins.
·
Doxycycline
at recommended doses does not accumulate significantly in patients with renal failure
and thus is one of the safest of the
tetracyclines for use in patients with renal impairment. The drug is
excreted in the feces.
·
Because of its short half-life, TOLBUTAMIDE is the safest
sulfonylurea for elderly diabetics.
·
The safest laxatives
for chronic use include the bulk
formers and stool softeners.
·
Nitrous oxide
is safest of inhalational anaesthetics.
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